@feloneouscat Privoxy? This would be system wide. It can be set and forget or extensively configured to taste. I've used it but wanted something sitewide so I use AdGuard in DNS mode -- it blackholes ad traffic.
Neither of these are Safari-specific but they'll work fine w/MacOS setups.
https://www.privoxy.org/
https://adguard.com/en/welcome.html
@b4cks4w
Back a long time ago I used Privoxy. I guess it’s time to experiment again.