Gastrointestinal diseases often come with a dose of pain, in addition to disruptive digestive issues. Eating the wrong food, or too much of the right one, can cause a stomachache. Those gut feelings are driven by enteric nerve cells, including glia.
https://www.quantamagazine.org/in-the-guts-second-brain-key-agents-of-health-emerge-20231121/
@johnverdon I very much get that feeling from my Gastroenterologist