#MS In the UK one of the research projects in the UK MS Register. It is a collaboration between the MS Society and Swansea University Medical School. You sign forms and then they have access to your medical data. The site records certain information and asks you to complete questionnaires that are compared over time. It can also introduce you to other research studies.

https://ukmsregister.org/AboutUs

Research Priorities: Pathways to Multiple Sclerosis Cures #MS https://www.nationalmssociety.org/NationalMSSociety/media/MSNationalFiles/Research/Pathways_To_Cures_Executive_Summaries.pdf

Exercise-induced increase in blood-based brain-derived neurotrophic factor (BDNF) in people with #MS : A systematic review and meta-analysis of exercise intervention trials https://journals.plos.org/plosone/article

Octopus multi-arm, multi-stage trial for progressive #MS

https://www.mssociety.org.uk/research/explore-our-research/research-we-fund/search-our-research-projects/octopus

I take part in this as well as 1 more around covid-19 and MS and 1 more around just covid-19

UK MS Register Sub-study: The impact of COVID-19 on people with #MS

https://www.mssociety.org.uk/research/explore-our-research/research-we-fund/search-our-research-projects/uk-ms-register-sub

Simvastatin is used to treat high cholesterol, but has also shown promise in #MS. It’s being tested in a phase 3 clinical trial. https://www.mssociety.org.uk/research/explore-our-research/emerging-research-and-treatments/explore-treatments-in-trials/simvastatin

Researchers discover changing a single gene can boost myelin repair in older mice https://www.mssociety.org.uk/research/latest-research/latest-research-news-and-blogs/researchers-discover-changing-single-gene-can-boost-myelin-repair-older-mice #MS

#MS This research is applicable to MS drugs - should a person be moved to another drug as their current one is being fought by their immune system (and could also work for another there chronic illness).

GloBody Technology: Detecting Anti-Drug Antibody against VH/VL domains https://www.nature.com/articles/s41598-020-58041-3#

Just had the report from my November MRI - Stable appearances. No new lesions. The next one will happen in March.

#MS

If you have or know anyone with #MS they will find this fascinating. It also points the way of how this cause can be eliminated in the future.

More evidence that EBV is the cause of MS https://gavingiovannoni.substack.com/p/more-evidence-that-ebv-is-the-cause

What joy - I've just be sent an MRI for 11th March - something to look forward to. 🙄 (My last one was mid November). To add context they watch me carefully because I a) have MS b) am given a drug which could cause PML (Tysabri) c) I am JC Vrus positive and d) have taken it for over 5 years and my risk of PML goes up the longer I take it. BUT it is a DMD (disease modifying drug) and I will have 70% fewer relapses and should therefore deteriorate slower. (so worth the risk). #MS

UK - MS and COVID-19: Two new treatments available from mid-December https://www.mssociety.org.uk/what-we-do/news/ms-and-covid-19-two-new-treatments-available-mid-december

#MS #covid19 #covid

Tokyo Paralympics: Kadeena Cox sets new world record to win gold https://www.bbc.co.uk/sport/disability-sport/58352830 Kadeena has #MS and is an ambassador for the UK MS Society. Here is an interview with her about her MS https://mstrust.org.uk/news/views-and-comments/kadeena-cox-ms-doesnt-put-a-full-stop-after-your-name

Christina Applegate reveals she has Multiple Sclerosis: 'It's been a strange journey' https://news.sky.com/story/christina-applegate-reveals-she-has-multiple-sclerosis-its-been-a-strange-journey-12378006 #MS

Machine learning identifies new subtypes of MS from MRI scans https://mstrust.org.uk/research/research-updates/210513-machine-learning-identifies-new-subtypes-ms-mri-scans #MS

UK to test existing drugs as treatment for MS in world-first trial https://www.theguardian.com/society/2021/mar/22/uk-to-test-existing-drugs-as-treatment-for-ms-in-world-first-trial #MS

Caroline Wyatt: MS research 'the urgent search for hope' https://www.bbc.co.uk/news/health-55360928 #MS

I had a fairly detailed conversation with my Mum yesterday around coronavirus vaccines, T-cells, MS disease-modifying drugs and possible interactions. Still feeling weird considering neither of us has any science type qualifications past the basic school stuff. lol (my conclusions to her being there is risk that one could interfere with the other due to too many things doing stuff with t-cells at the same time and I need to be very careful which one I have when it is available.) #MS

Multiple sclerosis patient's home renovated by friends https://www.bbc.co.uk/news/av/uk-england-hampshire-54024004 What amazing friends #MS

This is part 1 of a 2 part series.

MS Trust - Should I be preparing now in case I catch coronavirus?https://www.mstrust.org.uk/news/views-and-comments/should-i-be-preparing-now-case-i-catch-coronavirus #MS #covid19