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Psilocybin—the hallucinogen in magic mushrooms—continues to show promise as an anti-depressant, especially when combined with psychotherapy. Meanwhile though, it's being explored for treating anxiety, OCD, irritable bowel syndrome, and other disorders.
https://www.nature.com/articles/s44220-024-00332-z.epdf
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@thewebrecluse when chemically isolated, does it still cause nausea? I tried them once and was miserable with stomach upset. How that could help IBS seems wonky.
Two phase 2 clinical trials showing its efficacy in helping with hostility, somatization (the physical expression of psychological distress), and interpersonal sensitivity (heightened awareness of others' perceptions and reactions) led to University of Toronto researchers to call for a broader reframing of psilocybin-based treatments.
In a new Nature Mental Health scientific paper, they suggest calling psilocybin an "anti-distressant."