There was a good segment on the history of anti-vax on CBS Sunday Morning. Brief, but they traced it all the way to reluctance (understandable) to take the original smallpox inoculation. (It involved cutting you and smearing ground up scabs, etc. In wound. And everybody got sick, ans some even died.) But it was still better than your odds if you actually got smallpox.
Ben Franklin regretted not getting it for his grandson in fear of it. But he got smallpox and died.
Of course, the story traced general trend toward acceptance until the political football around Covid vaccine.
RFK Jr. Is directly accountable for a measles outbreak in Samoa.
83 people died.
Two infants died after "getting the vaccine" to start it, but that was revealed to be a nurse getting it mixed up with muscle relaxant.
RFK Jr.fanned the flames AFTER he knew the truth and denied accountability for his part in the outbreak and resultant deaths.