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Heads up for all you mentally healthy folks.
When a person has a major depressive cycle or when they seemingly crash it is NOT the most recent thing that caused it.
It is almost always the result of a house of cards toppling. What brought this on may be as small as spilling their drink. But it starts a chain reaction neither you nor they can't stop. You can't see the whole emotional catastrophe in progress. They probably can't right then either.
Offer support and love.